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Bravecto Chewable Tablets

Bravecto Chewable Tablets for Dogs are indicated for the treatment of flea and tick infestations in dogs for up to 12 weeks. They eliminate up to 99% of fleas and ticks within 8-12 hours and 100% of them within the 12 week period. They are also indicated for the treatment of demodicosis caused by Demodex canis, and for the treatment of sarcoptic mange (sarcoptes scabiel var. canis) infestation.

Bravecto Chewable Tablets are light to dark brown in colour, and round with a smooth or slightly rough surface. Some marbling, speckles or both may be visible.

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Bravecto 1000mg Chewable Tablets for Large Dogs

Bravecto 1000mg Chewable Tablets for Large Dogs

£24.49

Bravecto 1000mg Chewable Tablets are an innovative treatment for flea and tick infestations in dogs weighing 20 - 40kg. Containing an extoparasticide called Fluralaner that works quickly...[More info]

£24.49
Bravecto 500mg Chewable Tablets for Medium Dogs

Bravecto 500mg Chewable Tablets for Medium Dogs

£22.58

Bravecto 500mg Chewable Tablets are an innovative treatment for flea and tick infestations in dogs weighing 10 - 20kg. Containing an extoparasticide called Fluralaner that works quickly and...[More info]

£22.58
Bravecto 250mg Chewable Tablets for Small Dogs

Bravecto 250mg Chewable Tablets for Small Dogs

£21.28

Bravecto 250mg Chewable Tablets are an innovative treatment for flea and tick infestations in dogs weighing 4.5 - 10kg. Containing an extoparasticide called Fluralaner that works quickly...[More info]

£21.28
Bravecto 1400mg Chewable Tablets for Extra Large Dogs

Bravecto 1400mg Chewable Tablets for Extra Large Dogs

£28.84

Bravecto 1400mg Chewable Tablets are an innovative treatment for flea and tick infestations in dogs weighing 40 - 56kg. Containing an extoparasticide called Fluralaner that works quickly...[More info]

£28.84
Bravecto 112.5mg Chewable Tablets for Toy Dogs

Bravecto 112.5mg Chewable Tablets for Toy Dogs

£19.97

Bravecto 112.5mg Chewable Tablets are an innovative treatment for flea and tick infestations in dogs weighing 2 – 4.5kg. Containing an extoparasticide called Fluralaner that works...[More info]

£19.97

Contra-indications
Do not use in cases of hypersensitivity to the active substance or to any of the excipients.

Special warnings for each target species
Parasites need to start feeding on the host to become exposed to fluralaner; therefore the risk of the transmission of parasite borne diseases cannot be excluded.

Special precautions for use
Special precautions for use in animals
Use with caution in dogs with pre-existing epilepsy.
In the absence of available data, the veterinary medicinal product should not be used on puppies less than 8 weeks old and /or dogs weighing less than 2 kg.
The product should not be administered at intervals shorter than 8 weeks as the safety for shorter intervals has not been tested.

Operator warnings
Keep the product in the original packaging until use, in order to prevent children from getting direct access to the product.
Hypersensitivity reactions in humans have been reported.
Do not eat, drink or smoke while handling the product.
Wash hands thoroughly with soap and water immediately after use of the product.

Adverse reactions
Mild and transient gastrointestinal effects such as diarrhoea, vomiting, inappetence, and drooling were commonly observed in clinical trials (1.6% of treated dogs).
Convulsions and lethargy has been reported very rarely in spontaneous reports.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).

Use during pregnancy, lactation or lay
The safety of the veterinary medicinal product in breeding, pregnant and lactating dogs has been demonstrated. Can be used in breeding, pregnant and lactating dogs.
Interaction with other medicinal products and other forms of interaction
Fluralaner is highly bound to plasma proteins and might compete with other highly bound active substances such as non-steroidal anti-inflammatory drugs (NSAIDs) and the coumarin derivative warfarin. Incubation of fluralaner in the presence of carprofen or warfarin in dog plasma at maximum expected plasma concentrations did not reduce the protein binding of fluralaner, carprofen or warfarin.
During clinical field testing, no interactions between Bravecto chewable tablets for dogs and routinely used veterinary medicinal products were observed.
During clinical field testing, no interactions between Bravecto chewable tablets for dogs and routinely used veterinary medicinal products were observed.

Amounts to be administered and administration route
For oral use.
The chewable tablets should not be broken or divided.
For dogs above 56 kg body weight, use a combination of two tablets that most closely matches the bodyweight.
Method of administration
Administer Bravecto chewable tablets at or around the time of feeding.
Bravecto is a chewable tablet and is well accepted by most dogs. If the tablet is not taken up voluntarily by the dog it can also be given with food or directly into the mouth. The dog should be observed during administration to confirm that the tablet is swallowed.
Treatment schedule
For optimal control of flea infestation, the veterinary medicinal product should be administered at intervals of 12 weeks. For optimal control of tick infestation, the timing of retreatment depends on the tick species. See also section "Indications for use".
For the treatment of Demodex canis mite infestations, a single dose of the product should be administered. As demodicosis is a multi-factorial disease, it is advisable to also treat any underlying disease appropriately.
For the treatment of sarcoptic mange infestations (Sarcoptes scabiei var. canis), a single dose of the product should be administered. The need for and frequency of re-treatment should be in accordance with the advice of the prescribing veterinarian.

Overdose (symptoms, emergency procedures, antidotes), if necessary
No adverse reactions were observed following oral administration to puppies aged 8 – 9 weeks and weighing 2.0 – 3.6 kg treated with overdoses of up to 5 times the maximum recommended dose (56 mg, 168 mg and 280 mg fluralaner/kg body weight) on three occasions at shorter intervals than recommended (8-week intervals).
There were no findings on reproductive performance and no findings of concern on offspring viability when fluralaner was administered orally to Beagle dogs at overdoses of up to 3 times the maximum recommended dose (up to 168 mg/kg body weight of fluralaner).
The veterinary medicinal product was well tolerated in Collies with a deficient multidrug-resistance-protein 1 (MDR1 -/-) following single oral administration at 3 times the recommended dose (168 mg/kg body weight). No treatment-related clinical signs were observed.

Withdrawal periods
Not applicable.