Propentofylline Tablets for Dogs are for the improvement of dullness, lethargy and overall demeanour in dogs. They are particularly suitable for older dogs to help increase tolerance and willingness to exercise, Propentofylline has also been shown to increase the blood flow, particularly to the heart and skeletal muscle. It also increases the blood flow to the brain and therefore its oxygen supply, without increasing the brain's glucose demand. The tablets are available in 2 sizes: 50mg Tablets and 100mg Tablets.

Dosage & Administration

Propentofylline 50 mg tablets
Half tablet per 5kg body weight twice a day (equivalent to 6-10 mg propentofylline per kg bodyweight per day).
Dogs of less than 5kg may receive quarter tablet twice a day.
Dogs of more than 20kg can be given Propentofylline 100mg Tablets.

Propentofylline 100 mg tablets
Half tablet per 10kg body weight twice a day.
The tablets should not be quartered. More accurate dosing may be achieved using a combination of 100mg and 50mg tablets.
Dogs of less than 20kg can be given 50mg tablets.

The tablets can be administered directly onto the back of the dog's tongue or can be mixed in a small ball of food and should be administered at least 30 minutes before feeding.
Any remaining halved tablet portions should be discarded.

Contraindictions, Warnings etc
Do not administer to pregnant bitches or breeding animals.
Specific diseases (e.g. kidney disease) should be treated accordingly.
Consideration should be given to rationalising the medication of dogs already receiving treatment for congestive heart failure or bronchial disease.

Operator warnings:
Care should be taken to avoid accidental ingestion. In the event of accidental ingestion, seek immediate medical advice and show the package leaflet to the doctor.
Wash hands after use.

Pharmaceutical Precautions
Do not store above 25°C. Store in a dry place. Keep blister packs in outer carton.
Any unused product or waste materials should be disposed of in accordance with national requirements.

Further Information
Propentofylline has been shown to increase blood flow, particularly of the heart and skeletal muscle. It also increases the blood flow of the brain and therefore its oxygen supply, without increasing the brain's glucose demand. It has modest positive chronotropic effect and a marked positive ionotropic effect. In addition, it has been shown to have an anti-arrhythmic effect in dogs with myocardial ischemia and a bronchodilator action equivalent to that of aminofylline.
Propentofylline inhibits platelet aggregation and improves the flow properties of erythrocytes. It has a direct effect on the heart and reduces peripheral vascular resistance thereby lowering cardiac load.

For Animal Treatment Only
Keep out of reach and sight of Children