Vidalta Tablets can be used as treatment for hyperthyroidism and hyoerthyroidism-associated clinical signs in cats. Vidalta tablets are round pinktablets with white spots, available in 10mg and 15mg tablets.
- Aquarium Supplies
- Pond Supplies
- Wild Bird Supplies
- Caged Bird Supplies
- Pet Dental Care
- Ear Products
- Eye Products
- Feliway Products
- Flea Treatments
- Puppy Supplies
- Dog Supplements Cat Supplements
- Veterinary Diets
- Dog Food
- Dog Accessories
- Dog Grooming
- Dog Toys
- Dog Behaviour
- Dog Treats
- Dog Training Aids
- Kitten Supplies
- Cat Accessories
- Cat Grooming
- Cat Toys
- Cat Treats
- Cat Food
- Dog Worming & Cat Worming
- Horse Supplies
- Rabbit Supplies
- Guinea Pig Supplies
- Hamster Rat Chinchilla
- Ferret Supplies
- Pet Meds (Prescription Only)
- Veterinary Supplies
|Item name ascending [X]||Sort by price|
Vidalta 10mg Tablets. Please enter the quantity of tablets as per your prescription into the "add to cart" box below. [More info]
Vidalta 15mg Tablets. Please enter the quantity of tablets as per your prescription into the "add to cart" box below. [More info]
Vidalta 10 mg tablets for cats and Vidalta 15 mg tablets for cats.
10 mg tablet: Round pink tablet with little spots. Each tablet contains 10 mg carbimazole as active ingredient. Colouring agent: Red ferric oxide (E172): 0.25 mg.
15 mg tablet: Round dark pink tablet with little spots. Each tablet contains 15 mg carbimazole as active ingredient. Colouring agent: Red ferric oxide (E172): 0.75 mg.
Treatment of hyperthyroidism and hyperthyroidism-associated clinical signs in cats.
For oral use only. Vidalta tablets should be administered at the same time every day, in particular with relation to feeding. Do not break or crush Vidalta tablets as this will affect the sustained release property.
The aim of treatment is to maintain total thyroxine concentrations (TT4) in the lower end of the reference range. Accordingly, the following dose recommendations for dosing during adjustment and maintenance phases are suggested. However dosing adjustment should be primarily based upon the clinical assessment of the individual cat. Monitoring of TT4, full haematology and liver and kidney parameters is advised at each recommended follow up visit.
The starting dose is a single daily oral administration of one tablet of 15 mg carbimazole per cat. Consideration could be given to a starting dose of Vidalta 10 mg daily where the TT4 concentration is only mildly increased, e.g. between 50 nmol/L and 100 nmol/L.
With the recommended starting dose of one Vidalta 15 mg tablet once daily, total thyroxine concentration (TT4) may decrease to within the euthyroid range (TT4
Dose adjustment should also be performed 3, 5 and 8 weeks after initiation of treatment, depending on both clinical and hormonal responses to treatment. Follow-up visits every 3 to 6 months are recommended. The dose should be adjusted individually based on clinical signs and total thyroxine concentration (TT4). It is advisable to check TT4 10-14 days after dose adjustment.
The therapeutic dose of Vidalta ranges between 10 mg (one 10 mg tablet) and 25 mg (one 10 mg tablet and one 15 mg tablet) once daily.
Some cats require doses of less than 10 mg carbimazole daily. Every other day dosing with 10 mg or 15 mg of carbimazole may be sufficient to control the disease. Dose increases should not be made in increments of greater than 5 mg. Doses above 20 mg have only been trialled in a small number of cats and should be used with caution. Do not use in cats with haematological disorders, such as anaemia, neutropenia, lymphopenia or thrombocytopenia. Do not use in cats with coagulopathies.
Do not use in pregnant or lactating queens. Do not use in cats with hypersensitivity to mercaptoimidazoles (carbimazole or methimazole) Methimazole, the active metabolite of carbimazole, inhibits thyroid hormone production and therefore cessation of treatment with carbimazole will result in a rapid (within 48 hours) return to pre-treatment thyroid hormone levels. Chronic administration is therefore necessary unless surgical or radiation-induced thyroidectomy is performed. A small proportion of cats with thyroid adenoma may fail to respond or have a poor response to treatment. Thyroid carcinoma is a rare cause of hyperthyroidism in the cat and medical management alone is not recommended in such cases as it is not curative
Most frequent common adverse reactions encompass vomiting, diarrhoea, reduced appetite, loss of condition, lethargy, tachycardia, polydipsia, dehydration, and polyuria. Dermatological signs (pruritus, moist dermatitis, erythema, alopecia) have also been reported. These clinical signs are usually mild, adequately controlled by symptomatic therapy and do not require treatment discontinuation. In some cases, signs of gastrointestinal bleeding such as bloody vomit, oral haemorrhage or dark feces can be observed. These signs should be considered as serious and require immediate action (dose reduction or treatment discontinuation).
Weight loss, dyspnoea, aggressiveness, disorientation, ataxia or pyrexia have also been reported in rare cases.
Treatment of hyperthyroidism may result in a reduction in the glomerular filtration rate. This can lead to unmasking of pre-existent renal dysfunction. Renal function should therefore be monitored (BUN and creatinine) before and during treatment, preferably at each visit of the dose adjustment and maintenance phases. The dose should be adjusted according to the risk:benefit assessment for the individual case.
Treatment of hyperthyroidism with carbimazole may also induce an elevation of liver enzymes (AP and ALT) or a worsening of pre-existing hepatic disorders. Liver enzymes should therefore be monitored before and during treatment, preferably at each visit of the dose adjustment and maintenance phases. Severe cases may require temporary or permanent treatment discontinuation. Liver enzyme elevations are usually reversible following drug discontinuation, although symptomatic therapy (nutritional and fluid support) may be required.
Anaemia, increase or decrease in white blood cell count, neutrophilia, thrombocytopaenia, eosinophilia and/or lymphopenia may also occur, in particular during the first 4-6 weeks of treatment. Haematology parameters should therefore be monitored on a regular basis before and during treatment, preferably at each visit of the dose adjustment phase and maintenance phase. Treatment discontinuation may be required in case of persistent and marked disorder. In most of the cases, the abnormality will resolve spontaneously within 1 month after treatment discontinuation. Positive antinuclear antibodies titres have also been reported.
Doses above 20 mg have only been trialled in a small number of cats. Adverse reactions may occur at this dose, therefore careful monitoring is recommended and the dose should be adjusted according to the risk:benefit assessment for the individual case. Concomitant treatment with phenobarbitone may reduce the clinical efficacy of carbimazole. The concomitant use of benzimidazole anthelmintics (fenbendazole or mebendazole) has been shown to reduce the hepatic oxidation of this therapeutic class and may therefore induce an increase of their circulating rates. Accordingly, co-administration of carbimazole with a benzimidazole is not recommended. Methimazole may display immunomodulating properties. This should be taken into account when considering vaccination of the cat. In case of overdosage, adverse effects that may appear include, but are not limited to, weight loss, inappetence, vomiting, lethargy and less frequently signs of gastrointestinal bleeding such as haematemesis, oral haemorrhage, or haemorrhage of the intestinal tract. Coat and skin abnormalities (erythema, alopecia), as well as haematological/biochemical changes (eosinophilia, lymphocytosis, neutropaenia, lymphopaenia, slight leucopaenia, agranulocytosis, thrombocytopaenia or haemolytic anaemia) may also appear. Hepatitis and nephritis have been reported. These adverse effects may become severe in case of chronic overdosing. In most cases, adverse effects are reversible upon treatment discontinuation and appropriate veterinary care.
Total thyroxin concentrations (TT4) below the lower limit of the reference range may be observed during treatment although this is rarely linked to overt clinical signs. Decreasing the dose will lead to an increase of the TT4. Dose adjustment should not be made based on TT4 only.
The safety of the veterinary medicinal product has not been established in pregnant or lactating queens. However, since methimazole crosses the placenta, distributes into milk and reaches approximately the same concentration as in maternal serum, the product should not be used in pregnant or lactating queens. Operator warnings: In the case of accidental ingestion, seek medical advice immediately and show the package leaflet or the label to the physician.
Wash hands with soap and water after handling litter used by treated animals. Do not eat, drink or smoke while handling the tablet or used litter.
Do not handle this product if you are allergic to hyperthyroidism inhibitors. As carbimazole is a suspected human teratogen, women of child-bearing age should wear gloves when handling litter and/or vomit of treated cats. For animal treatment only. Keep out of reach and sight of children.
The tablets should be dispensed in their original packs. Do not store above 25°C. Protect from humidity and light. Keep the plastic container tightly closed to protect from moisture. Do not remove the desiccant.
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.
- About Us
- Privacy and Security
- Terms and Conditions
- VetUK Charity Programme
- Website FAQ`s
- Site Map
- Copyright VetUK 2005-2013
- VetUK Ltd, Units 7 & 8 Europark, Station Road, Thirsk, YO7 1GQ
- VetUK Reviews
- Registered with the R.C.V.S. Registration Number 6588469
- Registered with the V.M.D. Registration Number 2028468
- VetUK Pet Insurance