Soloxine are small elliptical tablets containing L-Thyroxine Sodium. Scored on the face of each tablet, strength in milligrams to the right and the word Soloxine on the reverse. 0.1 mg yellow, 0.2 mg orange, 0.3 mg green, 0.5 mg white, 0.8 mg blue. Soloxine can be used for the long term treatment of thyroid insufficiency in dogs. L-Thyroxine is a synthetic product chemically identical to the naturally occurring thyroid hormone `T4'. Its effect is slow in onset, but of long duration.

Soloxine dosage should be adjusted for the individual case based on the response of the patient and laboratory investigations, and should be administered daily. Pharmacokinetic trials demonstrate that once daily dosing gives higher blood levels than dividing the daily dose over the day.

The commonly prescribed soloxine dose is 22 µg/kg bodyweight/day. This is frequently too low, and doses of up to 44 µg/kg bodyweight/day may be required. Appropriate laboratory tests should be conducted to confirm the diagnosis and ensure correct dosage. For oral administration.

Do not use soloxine in dogs with thyrotoxicosis or uncorrected adrenal insufficiency. The effects of Thyroxine therapy are slow in being manifested. Administer with caution to animals with clinically significant heart disease, hypertension or other complications for which a sharply increased metabolic rate might prove hazardous.

Chronic overdosage of soloxine will eventually lead to thyrotoxicosis, manifested by: panting, nervousness, tachycardia, aggressive behaviour, polyuria, polydipsia, polyphagia and weight loss. If you notice any serious effects or other effects not mentioned in the leaflet, please inform your veterinary surgeon. Wash hands after use.

In case of accidental ingestion, seek medical advice immediately and show the doctor the leaflet. General precautions: For animal treatment only. Keep out of the reach and sight of children. Do not store above 25°C. Protect from light. Dispose of used packaging in the household refuse. Unused product should be returned to the veterinary surgeon.