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Kesium Chewable Tablets

Kesium Chewable Tablets are for the treatment of infections caused by ß-lactamase producing strains of bacteria sensitive to amoxicillin in combination with calvulanic acid and where clinical experience and/or sensitivity testing indicates the product as the drug of choice. The tablets are beige in colour, oblong and have an equal break line. They are available in 4 sizes: Kesium 50mg, Kesium 62.5mg, Kesium 250mg and Kesium 500mg.

Kesium 50mg Chewable Tablets for Cats and Dogs

Kesium 50mg Chewable Tablets for Cats and Dogs

£0.14

Kesium Chewable Tablets are for the treatment of infections caused by ß-lactamase producing strains of bacteria sensitive to amoxicillin in combination with clavulanic acid and where...[More info]

£0.14
Kesium 62.5mg Chewable Tablets for Cats and Dogs

Kesium 62.5mg Chewable Tablets for Cats and Dogs

£0.18

Kesium Chewable Tablets are for the treatment of infections caused by ß-lactamase producing strains of bacteria sensitive to amoxicillin in combination with clavulanic acid and where...[More info]

£0.18
Kesium 250mg Chewable Tablets for Dogs

Kesium 250mg Chewable Tablets for Dogs

£0.37

Kesium Chewable Tablets are for the treatment of infections caused by ß-lactamase producing strains of bacteria sensitive to amoxicillin in combination with clavulanic acid and where...[More info]

£0.37
Kesium 500mg Chewable Tablets for Dogs

Kesium 500mg Chewable Tablets for Dogs

£0.74

Kesium Chewable Tablets are for the treatment of infections caused by ß-lactamase producing strains of bacteria sensitive to amoxicillin in combination with clavulanic acid and where...[More info]

£0.74
Kesium 625mg Chewable Tablets for Cats and Dogs

Kesium 625mg Chewable Tablets for Cats and Dogs

£1.00

Kesium Chewable Tablets are for the treatment of infections caused by ß-lactamase producing strains of bacteria sensitive to amoxicillin in combination with clavulanic acid and where...[More info]

£1.00

Target Species:
50 and 62.5 mg tablets - cats and dogs
250 and 500 mg tablets - dogs

Indications for Use, Specifying the Target Species:
For the treatment of the following infections caused by β lactamase producing strains of bacteria sensitive to amoxicillin in combination with clavulanic acid and where clinical experience and/or sensitivity testing indicates the product as the drug of choice:
    - Skin infections (including superficial and deep pyodermas) associated with Staphylococcus spp.
    - Urinary tract infections associated with Staphylococcus spp, Streptococcus spp, Escherichia coli and Proteus mirabilis.
    - Respiratory tract infections associated with Staphylococcus spp, Streptococcus spp and Pasteurella spp.
    - Digestive tract infections associated with Escherichia coli.
    - Infections of the oral cavity (mucous membrane) associated with Pasteurella spp, Streptococcus spp, Escherichia coli.

Contraindications
Do not use in animals with known hypersensitivity to penicillins or other susbstances of the β-lactam group or to any excipients.
Do not use in animals with serious dysfunction of the kidneys accompanied by anuria and oliguria.
Do not administer to gerbils, guinea pigs, hamsters, rabbits and chinchillas. Do not use in horses and ruminating animals.
Do not use where resistance to this combination is known to occur.

Special Warnings for each target species
None known

Special Precautions for Use
i) Special precautions for use in animals

Official, national and regional antimicrobial policies with respect to the use of broad-spectrum antibiotics should be taken into account.
Do not use in case of bacteria sensitive to narrow spectrum penicillins or to amoxicillin as single substance.
It is advised that upon initiating therapy appropriate sensitivity testing is performed and that therapy is continued only after susceptibility to the combination has been established.
Use of the product deviating from the instructions given in the SPC may increase the prevalence of bacteria resistant to the amoxicillin/clavulanate, and may decrease the effectiveness of treatment with beta-lactam antibiotics
In animals with hepatic and renal dysfunction, the dosing regimen should be carefully evaluated and the use of the product based on a risk/benefit evaluation by the veterinary surgeon.
Caution is advised in the use in small herbivores other than those in the section 4.3.
The potential for allergic cross-reactions with other penicillin derivates and cephalosporins should be considered

ii) Special precautions to be taken by the person administering the veterinary medicinal product to animals
Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross-reactions to cephalosporins and vice versa. Allergic reactions to these substances may occasionally be serious.
Do not handle this product if you know you are sensitised, or if you have been advised not to work with such preparations.
Handle this product with great care to avoid exposure, taking all recommended precautions.
If you develop symptoms following exposure such as a skin rash, you should seek medical advice and show the doctor this warning. Swelling of the face, lips or eyes or difficulty with breathing are more serious symptoms and require urgent medical attention.
Wash hands after use.

Adverse Reactions (Frequency and Seriousness)
Mild gastrointestinal signs (diarrhoea, and vomiting) may occur after administration of the product. Treatment may be discontinued depending on the severity of the undesirable effects and a benefit/risk evaluation by the veterinary surgeon.
Allergic reactions (skin reactions, anaphylaxis) may occasionally occur. In these cases, administration should be discontinued and a symptomatic treatment given.

Use during Pregnancy, Lactation or Lay
Laboratory studies in rats and mice have not produced any evidence of teratogenic, foetotoxic or maternotoxic effects.
In pregnant and lactating animals, use only according to the benefit/risk assessment by the responsible veterinarian.

Interaction with other Medicinal Products and Other Forms of Interaction
Chloramphenicol, macrolides, sulfonamides and tetracyclines may inhibit the antibacterial effect of penicillins because of the rapid onset of bacteriostatic action.
Penicillins may increase the effect of aminoglycosides.