Ceporex Vet film-coated tablets for dogs are a broad spectrum cephalosporin antibiotic with bactericidal activity against a wide range of gram-positive and gram-negative bacteria. Round, convex, pink film-coated tablets embossed with "Ceporex 50" "Ceporex 250" "Ceporex 500" on one side. Available in Ceporex 50mg, Ceporex 250mg and Ceporex 500mg.

Ceporex Tablets are indicated for oral antibiotic therapy in dogs. Cefalexin is a broad spectrum cephalosporin antibiotic with bactericidal activity against a wide range of Gram-positive and Gram-negative bacteria.

The following micro-organisms have been shown to be sensitive to cefalexin in vitro: Staphylococcus spp. (including penicillin-resistant strains), Streptococcus spp., Corynebacterium spp., Pasteurella multocida, Escherichia coli, Micrococcus spp, Moraxella spp.

When susceptible organisms are present, the tablets may be effective in the treatment of infections of the respiratory tract, urogenital tract, the skin and localised infections in soft tissue.

In dogs Ceporex may also be effective in the treatment of infections of the gastrointestinal tract.

Cefalexin is rapidly, and almost completely, absorbed after oral administration. Effective blood levels are generally achieved within two hours of dosing. Cefalexin is excreted in the urine in a high concentration.

The recommended Ceporax dose rate is 10 to 15 mg/kg bodyweight twice daily.

The following is intended as a guide for dogs. treatment for five days is recommended

10 to 25 kg bodyweight: 1 x 250 mg tablet twice daily.
 
26 to 50 kg bodyweight: 2×250 mg tablets twice daily.
 
51 kg and over bodyweight: 3×250 mg tablets twice daily.

Any variation should be at the discretion of the prescribing veterinary surgeon, e.g. in cases where the condition requires an extended course of treatment (such as chronic pyoderma).

The tablets are well accepted by dogs but may be crushed or added to food if necessary.

Do not use Ceporax in animals which are known to be hypersensitive to cefalexin. Do not use in rabbits, guinea pigs, hamsters and gerbils.

The safety of the product has not been demonstrated in studies in pregnant or lactating dogs. Use only in accordance with benefit/risk assessment by the responsible veterinary surgeon.

Hypersensitivity to cefalexin is rare.

The administration of cefalexin has been shown to produce no serious side-effects at many times the recommended dose rate.

As with other antibiotics which are excreted mainly by the kidneys, unnecessary accumulation may occur in the body when renal function is impaired. In cases of known renal insufficiency the dose should be reduced and the product used in accordance with a benefit/risk assessment by the responsible veterinarian.

Use of the product should be based on susceptibility testing of the bacteria isolated from the animal. If this is not possible, therapy should be based on local epidemiological information about susceptibility of the target bacteria and take into account official, national and regional antimicrobial policies.

The use of antibiotics, especially penicillins and cephalosporins, has been associated with potentially fatal antibiotic enterotoxaemia, particularly in rabbits.

Cephalosporins may cause sensitisation (allergy) following injection, inhalation, ingestion or skin contact. Sensitivity to penicillin may lead to cross sensitivity to cephalosporin and vice versa. Allergic reactions to these substances may occasionally be serious.

Do not handle this product (or these products) if you know you are sensitised, or if you have been advised not to work with such preparations.

Handle Ceporex tablets with great care to avoid exposure, taking all recommended precautions.

If you develop symptoms following exposure such as a skin rash you should seek medical advice and show the doctor this warning. Swelling of the face, lips or eyes or difficulty with breathing are more serious symptoms and require urgent medical attention.

For animal treatment only. Keep out of the reach and sight of children. Do not store above 25°C. Protect from light.

Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.