Frontline for Large Dogs
Frontline for Large Dogs is a highly effective flea killing preparation containg Fipronil. Each pipette contains 2.68mls of fipronil which should be used for dogs weighing between 20Kg and 40Kg; when applied correctly the spot on solution will be effective against fleas for up to eight weeks. Frontline for Large Dogs is available in packets of three and six pipettes.
Frontline for Large Dogs 3 Pack is for use in the treatment and prevention of infestations by fleas and ticks. Frontline for Dogs can be used on puppies from 8 weeks of age. Apply...[More info]
Frontline for Large Dogs 6 Pack is for use in the treatment and prevention of infestations by fleas & ticks. Frontline for Dogs can be used on puppies from 8 weeks of age. Apply...[More info]
The active ingredient in frontline for Large dogs is Fipronil, a member of the phenylpyrazole family of non-systemic insecticides/acaricides, which acts by blocking the GABA receptor to kill the target parasite on contact. Frontline Spot-On for Large Dogs is effective against flea infestation for approximately two months and against tick infestation for up to one month, depending on the level of environmental challenge. Newly arriving fleas are killed within 24 hours of landing on the animal. Re-treatment may safely be carried out at one month intervals and is licensed for use as part of a strategy for the treatment of Flea Allergy Dermatitis. For this condition, monthly application to the allergic patient and to other dogs in the household is recommended.
Applying frontline does not prevent all ticks attaching to the animal, but ticks will be killed in the first 24 - 48 hours after attachment, prior to full engorgement and therefore minimising the risk of transmission of disease. Once dead, ticks will often drop off the animal, but any remaining ticks may easily be removed by a gentle pull, preferably using tweezers. There may be an attachment of single ticks. For this reason transmission of infectious diseases cannot be completely excluded if conditions are unfavourable.
Fleas from pets often infest the animal's basket, bedding and regular resting areas such as carpets and soft furnishings which should be treated, in case of massive infestation and at the beginning of the control measures, with a suitable insecticide and vacuumed regularly. When treating infestations of lice, all in-contact dogs should be treated with an appropriate product at the same time. Laboratory studies using fipronil have not shown any teratogenic or embryotoxic effect. The safety of the product was demonstrated in breeding, pregnant and lactating bitches treated with multiple consecutive doses with up to 3 times the maximum recommended dose. Frontline for large dogs can be used during pregnancy and lactation. No adverse effects were observed in target animal safety studies in 8-week old puppies, growing dogs and dogs weighing about 2 kg treated once at five times the recommended dose. The risk of adverse effects may increase when overdosing, so animals should always be treated with the correct pipette size according to bodyweight. Safety data are not available for use of the product in animals less than 8 weeks of age. After the topical application the product will spread from the site of treatment to cover the entire surface of the animal within 24 hours. After application, absorption of fipronil through the skin is slight.